The aim of the project is to investigate the use of CO2 and syngas (H2/CO) produced from biomass in metal-catalysed, direct and enantioselective carboxylation and carbonylation of styrenes for the production of high value fine chemicals of interest to the pharmaceutical industry. The production of pure CO2 and syngas will require (i) optimisation of pyrolysis, gasification, chemical looping combustion, separation and purification (link to Platform 1 – PP-1 and PP-2) (ii) test a range of ligands to determine both regioselectivity and enantioselectivity; (iii) extend alkene substrates to naturally occurring examples; (iv) apply methodology to compounds of pharmaceutical interest.